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    貞本和代2、坂本祐一郎2、門屋美知代1、末信敏秀2

    1 かどやアニマルホスピタル

    2 千寿製薬株式会社

    獣医臨床皮膚科27(1):11-19,2021

  • In vivo comet assay in rabbit corneal epithelial cells following ocular instillation with genotoxic compounds

    Haruna Tahara, Yoshinori Yamagiwa, Yu Haranosono and Masaaki Kurata

    Genes and Environment. 2021, 43:11.

  • Histological Features of Postnatal Development of the Eye in White Rabbits

    山際慶典１,２、倉田昌明１、佐藤洋２

    1 千寿製薬株式会社

    2 岩手大学大学院獣医学研究科

    Toxicologic Pathology 2021;49(3):419-437

  • Mechanical stretch induces Ca2+ influx and extracellular release of ­PGE2 through Piezo1 activation in trabecular meshwork cells

    Takatoshi Uchida1,2, Shota Shimizu1,2, ReikoYamagishi1, Suzumi M.Tokuoka3,Yoshihiro Kita3,4, Megumi Honjo1 & MakotoAihara1

    1 Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, 7‑3‑1, Hongo, Bunkyo‑ku, Tokyo 113‑8655, Japan.

    2 Senju Laboratory of Ocular Science, Senju Pharmaceutical Co., Ltd., Kobe, Japan.

    3 Department of Lipidomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

    4 LifeScience Core Facility, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

    Scientific Reports. 2021;11:4044

  • Ocular and systemic pharmacokinetics of brimonidine and brinzolamide after topical administration in rabbits: comparison between fixed-combination and single-drug formulations

    鈴木 源、國兼 絵里子、重見 稚紗、新野 啓介、香西 聖子、倉田 昌明、河村 章生

    Current Eye Research 2021;46(3):380-386

  • Investigation of in vivo unscheduled DNA synthesis in rabbit corneas following instillation of genotoxic agents

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    CUTANEOUS AND OCULAR TOXICOLOGY 2021, VOL. 40, NO. 1, 26–36

  • Ocular and systemic pharmacokinetics of brimonidine and timolol after topical administration in rabbits: comparison between fixed-combination and single drugs

    鈴木 源、國兼 絵里子、新野 啓介、香西 聖子、倉田 昌明、河村 章生

    Ophthalmology and Therapy 2020;9:115-125

  • Activation of Cytosolic Calpain, Not Caspase, Is Underlying Mechanism for Hypoxic RGC Damage in Human Retinal Explants

    Momoko Kobayashi-Otsugu,１,２ Kana Orihara,１,２ Emi Nakajima,１,２ Thomas R. Shearer,２ and Mitsuyoshi Azuma１,２

    １Senju Laboratory of Ocular Sciences, Senju Pharmaceutical Corporation Limited, Portland, Oregon, United States

    ２Department of Integrative Biomedical & Diagnostic Sciences, Oregon Health & Science University, Portland, Oregon,United States

    Investigate Ophthalmology & Visual Science.2020;61(13):13.

  • Segmenting OCT for detecting drug efficacy in CRAO

    Thomas R. ShearerID１, Thomas S. Hwang２, Peter N. Steinkamp２, Mitsuyoshi Azuma３

    １Department of Integrative Biomedical & Diagnostic Sciences, Oregon Health & Science University, Portland, OR, USA

    ２Department of Ophthalmology-OHSU, Portland, OR, USA

    ３Senju Laboratory of Ocular Sciences, Senju Pharmaceutical Co., Ltd, Portland, OR, USA

    PLoS ONE 15(12):e0242920.

  • ブリモニジン／ブリンゾラミド配合懸濁性点眼液の原発開放隅角緑内障（広義）または高眼圧症を対象とした第III相臨床試験－ブリモニジンとの比較試験

    相原 一１、関弥卓郎２

    １東京大学大学院医学系研究科外科学専攻眼科学

    ２千寿製薬株式会社

    あたらしい眼科37(10)：1289～1298,2020©

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