• 0.3% ロメフロキサシンのイヌ細菌性外耳炎に対する有効性と安全性に関する調査

    貞本和代2、坂本祐一郎2、門屋美知代1、末信敏秀2

    1 かどやアニマルホスピタル

    2 千寿製薬株式会社

    獣医臨床皮膚科27(1):11-19,2021

  • In vivo comet assay in rabbit corneal epithelial cells following ocular instillation with genotoxic compounds

    Haruna Tahara, Yoshinori Yamagiwa, Yu Haranosono and Masaaki Kurata

    Genes and Environment. 2021, 43:11.

  • Histological Features of Postnatal Development of the Eye in White Rabbits

    山際慶典１,２、倉田昌明１、佐藤洋２

    1 千寿製薬株式会社

    2 岩手大学大学院獣医学研究科

    Toxicologic Pathology 2021;49(3):419-437

  • Mechanical stretch induces Ca2+ influx and extracellular release of ­PGE2 through Piezo1 activation in trabecular meshwork cells

    Takatoshi Uchida1,2, Shota Shimizu1,2, ReikoYamagishi1, Suzumi M.Tokuoka3,Yoshihiro Kita3,4, Megumi Honjo1 & MakotoAihara1

    1 Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, 7‑3‑1, Hongo, Bunkyo‑ku, Tokyo 113‑8655, Japan.

    2 Senju Laboratory of Ocular Science, Senju Pharmaceutical Co., Ltd., Kobe, Japan.

    3 Department of Lipidomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

    4 LifeScience Core Facility, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

    Scientific Reports. 2021;11:4044

  • Ocular and systemic pharmacokinetics of brimonidine and brinzolamide after topical administration in rabbits: comparison between fixed-combination and single-drug formulations

    鈴木 源、國兼 絵里子、重見 稚紗、新野 啓介、香西 聖子、倉田 昌明、河村 章生

    Current Eye Research 2021;46(3):380-386

  • Investigation of in vivo unscheduled DNA synthesis in rabbit corneas following instillation of genotoxic agents

    Haruna Tahara, Shingo Nemoto, Yoshinori Yamagiwa, Yu Haranosono & Masaaki Kurata

    CUTANEOUS AND OCULAR TOXICOLOGY 2021, VOL. 40, NO. 1, 26–36

  • Ocular and systemic pharmacokinetics of brimonidine and timolol after topical administration in rabbits: comparison between fixed-combination and single drugs

    鈴木 源、國兼 絵里子、新野 啓介、香西 聖子、倉田 昌明、河村 章生

    Ophthalmology and Therapy 2020;9:115-125

  • Activation of Cytosolic Calpain, Not Caspase, Is Underlying Mechanism for Hypoxic RGC Damage in Human Retinal Explants

    Momoko Kobayashi-Otsugu,１,２ Kana Orihara,１,２ Emi Nakajima,１,２ Thomas R. Shearer,２ and Mitsuyoshi Azuma１,２

    １Senju Laboratory of Ocular Sciences, Senju Pharmaceutical Corporation Limited, Portland, Oregon, United States

    ２Department of Integrative Biomedical & Diagnostic Sciences, Oregon Health & Science University, Portland, Oregon,United States

    Investigate Ophthalmology & Visual Science.2020;61(13):13.

  • Segmenting OCT for detecting drug efficacy in CRAO

    Thomas R. ShearerID１, Thomas S. Hwang２, Peter N. Steinkamp２, Mitsuyoshi Azuma３

    １Department of Integrative Biomedical & Diagnostic Sciences, Oregon Health & Science University, Portland, OR, USA

    ２Department of Ophthalmology-OHSU, Portland, OR, USA

    ３Senju Laboratory of Ocular Sciences, Senju Pharmaceutical Co., Ltd, Portland, OR, USA

    PLoS ONE 15(12):e0242920.

  • ブリモニジン／ブリンゾラミド配合懸濁性点眼液の原発開放隅角緑内障（広義）または高眼圧症を対象とした第III相臨床試験－ブリモニジンとの比較試験

    相原 一１、関弥卓郎２

    １東京大学大学院医学系研究科外科学専攻眼科学

    ２千寿製薬株式会社

    あたらしい眼科37(10)：1289～1298,2020©

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