Toxicity of Topical Anti-glaucoma Agents to Stratified Human Cultivated Corneal Epithelial Sheets
- 橋本 友美１、臼井 智彦２、坪田 裕喜３、横尾 誠一４、山上 聡５
１ JR東京総合病院
２ 東京大学
３ JCHO東京新宿メディカルセンター
４ 京都府立医大
５ 日本大学 - Journal of Ocular Pharmacology & Therapeutics（JOPT) 2014 Dec 1; 30(10): 810–814.
Role of Glutathione Peroxidase 4 in Corneal Endothelial Cells
- 内田孝俊１,2、酒井 修2、今井浩孝3、上田高志1
1 東京大学医学部附属病院眼科・視覚矯正科
2 千寿製薬株式会社
3 北里大学薬学部衛生化学講座 - Current Eye Research 2017 Mar;42(3):380-385
Selecting Fuchs’ Patients for Drug Trials Involving Endothelial Cell Proliferation
- Thomas R. Shearer、Chamberlain D. Winston
OHSU - British Journal of Ophthalmology 2016 Nov 4;26(6):536-539
Hydrogel Ring for Topical Drug Delivery to the Ocular Posterior Segment
- 鹿村 悠子1、山崎 佳子2、 松永 透2, 佐藤 隆郎2，大鳥 聡1,3、東條 角治3
1 千寿製薬株式会社
2 株式会社シード
3 九州工業大学 - Current Eye Reseach, 2016; 41(5):653-661.
Delayed, oral pharmacological inhbition of calpains attenuates adverse post-infarction remodeling
- Marcos Poncelas ,Javier Inserte,David Aluja,Victor Hernando,Ursula Vilardosa,David Garcia-Dorado
Laboratory of Cardiovascular Diseases, Vall d'Hebron University Hospital and Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain - Cardiovascular Research (2017) 113, 950–961
Steroid-sparing effects of 0.1% tacrolimus eye drop for treatment of shield ulcer and corneal epitheliopathy in eyes with refractory allergic ocular diseases
- 宮崎 大
鳥取大学 - Ophthalmology 2017,124(3)287-294
Ocular Instillation Toxicity Study: Current Status and Points to Consider on Study design and Evaluation
- 倉田 昌明
- Fundamental Toxicological Sciences 2016,3(5),217-232
Galectin-3 Enhances ECM Associations and Wound Healing in Monkey Corneal Epithelium
- 藤井 敦子１、Thomas R. Shearer２
1 千寿製薬
２ OHSU - Experimental Eye Research 137 (2015) 71-78
A study for finding new phototoxicity descriptors related to potential energy
- 原ノ園 祐
- The Journal of Toxicological Science 2017,4(3),105-107
In silico ocular pharmacokinetic modeling: delivery of topical FK962 to retina
- Ayumi Mori １、Kakuji Tojo ２、Thomas R. Shearer ３
１ 千寿製薬
２ Laboratory of Ocular Drug Delivery System, Kyushu Institute of Technology, Fukuoka, Japan
３ Department of Integrative Biosciences, Oregon Health & Science University, Portland, OR - The Journal of Ocular Pharmacology and Therapeutics 2017,33(7),556-566
Blockade of exaggerated nucleocytoplasmic export averts paralysis and motor neuron death in a mouse model of chronic excitotoxicity
- Kaori Sugiyama１、Tomomi Aida１、Masatoshi Nomura２、Ryoichi Takayanagi２、Hanns U. Zeilhofer３、Kohichi Tanaka１
１ 東京医科歯科大学
２ 九州大学
３ Swiss Federal Institute of Technology Zurich - Nature Medicine 2017,37(36),8830-8844
Hypoxia activates calpains in the nerve fiber layer of monkey retinal explants
- 平田 真之1、Thomas R. Shearer 2
1 千寿製薬
２ Department of Integrative Biosciences, Oregon Health & Science University - Investigative Ophthalmology & Visual Scienc 2015,56(10)6049-6057
Activation of Microglia-Neuron Induced Bidirectional Cytotoxicity is Associated with Calpain Activation
- Maria Podbielska1、Arabinda Das1、Amena W. Smith1、Chauhan Ashok2、Swapan K. Ray2、Edward L. Hogan3、Naren L. Banik3
1 Medical University of South Carolina
2 University of South Carolina
3 Medical University of South Carolina - Ｇｌｉａ 2016,139,440-455
Calpain genetic disruption and HSP90 inhibition combine to attenuate mammary tumorigenesis
- Stacy Grieve、Yan Gao、Christine Hall、Peter A. Greer
Division of Cancer Biology and Genetics, Queen's University, Canada - Cancer Research 2016,36(15),2078-2088
イブジラスト点眼液0.01％
- 末信 敏秀
- アレルギーの臨床 2016,36(8),52-57
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