Publications2011

Comparative studies of HPLC-fluorometry and LC/MS method for the determination of N-acetylneuraminic acid as a marker of deteriorated ophthalmic solutions

  • Kinya Iwatsuka1, Shin-ichi Yasueda1, Eiji Bando1, Hiroyuki Fujii1, Takashi Terada1, Hiroya Okubo1, Hiroki Iwamoto2, Mitsuhiro Kinoshita2, Kazuaki Kakehi2
    1 Senju Pharmaceutical CO.,LTD., 2 Kinki University
  • Journal of Chromatography B 879 (2011) , 2866-2870

Involvement of calpain 2 in ionomycin-induced cell death in cultured mouse lens epithelial cells.

  • Takeshi Nakajima1, Thomas R. Shearer2, Mitsuyoshi Azuma1,2
    1 Senju Pharmaceutical Co., Ltd.
    2 Department of Integrative Biosciences, Oregon Health & Science University
  • Curr Eye Res. 2011 Oct;36(10):930-6

Calpain, not caspase, is the causative protease for hypoxic damage in cultured monkey retinal cells.

  • Emi Nakajima1,2, Katherine B. Hammond1, Jennifer L. Rosales1, Thomas R. Shearer2 and Mitsuyoshi Azuma1,2
    1 Senju Pharmaceutical Co.,Ltd
    2 Department of Integrative Biosciences, Oregon Health & Science University
  • Invest Ophthalmol Vis Sci. 2011 Sep 1;52(10):7059-67

Effects of Y-39983, a Selective Rho-Associated Protein Kinase Inhibitor, on Blood flow in Optic Nerve Head in Rabbits and Axonal Regeneration of Retinal Ganglion Cells in Rats

  • Tokushige H1, Waki M1, Takayama Y1, Tanihara H2.
    1 Senju Pharmaceutical Co., Ltd, 2 Kumamoto University
  • Current Eye Research. 2011;36(10):964-970

Clinical Application of Selective ROCK Inhibitor as Drug for Glaucoma

  • Hideki Tokushige
  • Japanese Journal of Ocular Pharmacology 25:47-50, 2011

Metabolic profiles of difluprednate in rabbit ocular tissues after instillation of difluprednate ophthalmic emulsion.

  • Tajika T1, Takahashi H1, Sakai Y1, Fujii H1, Isowaki A2, Sakaki H1.
    1 Senju Pharmaceutical Co., Ltd., 2 Senju USA, Inc.
  • Xenobiotica. 2010 Aug;40(8):569-77.

Ocular distribution of difluprednate ophthalmic emulsion 0.05% in rabbits.

  • Tajika T1, Isowaki A2, Sakaki H1.
    1 Senju Pharmaceutical Co. Ltd., 2 Senju USA, Inc.
  • J Ocul Pharmacol Ther. 2011 Feb;27(1):43-9.

Pharmacokinetic features of difluprednate ophthalmic emulsion in rabbits as determined by glucocorticoid receptor-binding bioassay.

  • Tajika T, Waki M, Tsuzuki M, Kida T, Sakaki H.
  • J Ocul Pharmacol Ther. 2011 Feb;27(1):29-34.

Development of an eyedrop container for improvement of instillation adherence

  • Tadashi Otsuka
    Senju Pharmaceutical CO.,LTD.
  • Journal of Human Life Engineering 12 (1) , 32-38

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