Publications2010

Calpain Inhibitor Drugs

  • M. Azuma 1 and T. R. Shearer 2
    1 Senju Pharmaceutical Co., Ltd. 2 Oregon Health Sciences University
  • Medical Science Digest: Vol.36, No. 3, p.25-31, 2010.

Efficacy and Safety of Prostamide Analog LUMIGAN® Ophthalmic Solution 0.03% for Glaucoma and Ocular Hypertension

  • Akemi Mizuno, Tomoyuki Wada, Hideki Tokushige and Mitsuyoshi Isaka
    Senju Pharmaceutical Co., Ltd.
  • Japanese Journal of Ocular Pharmacology 24:19-24, 2010

Effects of Pathological Conditions on Ocular Pharmacokinetics of Antimicrobial Drugs

  • Kayoko Ueda 1,2, Akira Ohtori 1 and Kakuji Tojo 2
    1 Senju Pharmaceutical Co., Ltd.
    2 Kyushu Institute of Technology
  • Chem. Pharm. Bull. 58 (10) 1301-1305 (2010)

Mechanism for carbachol-induced secretion of lacritin in cultured monkey lacrimal acinar cells.

  • A. Morimoto-Tochigi 1, R. D. Walkup 1, E. Nakajima 1, T. R. Shearer 2, M. Azuma 1
    1 Senju Pharmaceutical Co., Ltd.
    2 Oregon Health & Science University
  • Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4395-4406.

Patient selection criteria for pilot studies on amelioration of non-neovascular age-related macular degeneration.

  • M. Azuma 1, K. Chung 2, A. Fujii 1, T. R. Shearer 2
    1 Senju Pharmaceutical Co., Ltd.
    2 Oregon Health & Science University
  • J Ocul Pharmacol Ther. 2010 Aug;26(4):367-371.

Bepotastine besilate, a highly selective histamine H1 receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis

  • Tetsuo Kida, Atsuko Fujii, Osamu Sakai, Masahito Iemura, Ikuyo Atsumi, Tomoyuki Wada, Hideyuki Sakaki.
  • Experimental Eye Research. 2010;91(1):85-91.

Evaluation of ocular surface damage caused by topical application of 3% N-acetylcysteine ophthalmic solution in dogs

  • Tetsuo Kida1, Chie Fujii1, Tsuyoshi Higuchi2, Hideyuki Sakaki1, Kazumichi Ushio1, Shizuo Yamagata3
    1 Senju Pharmaceutical Co., Ltd.
    2 Mitsubishi Chemical Safety Institute Ltd.
    3 Yamagata Animal Hospital.
  • Animal Eye Research. 2008;27:17-22.

Mucoadhesive properties of chitosan-coated ophthalmic lipid emulsion containing indomethacin in tear fluid

  • Masazumi Yamaguchi 1, Kayoko Ueda 1, Akiharu Isowaki 1, Akira Otori 1, Hirofumi Takeuchi 2, Nobuyuki Ohguro 3, Kakuji Tojo 4
    1 Senju Pharmaceutical Co., Ltd.
    2 Department of Pharmaceutical Engineering, Gifu Pharmaceutical University
    3 Department of Ophthalmology and Visual Science, Osaka University
    4 Department of Biochemical Science and Engineering, Kyushu Institute of Technology
  • Biol. Pharm. Bull. 32 (7) 1266-1271

HUMAN AND NON-HUMAN PRIMATE LENSES CULTURED WITH CALCIUM IONOPHORE FORM {alpha}B-CRYSTALLIN LACKING THE C-TERMINAL LYSINE, A PROMINENT FEATURE OF SOME HUMAN CATARACTS

  • Emi Nakajima 1, Larry L. David 2, Michael A Riviere 3, Mitsuyoshi Azuma 1, and Thomas R. Shearer 3

    1 Senju Pharmaceutical Co., Ltd., Senju Laboratory of Ocular Sciences, Beaverton, Oregon, United States; Departments of Integrative Biosciences, Oregon Health Sciences University, Portland, Oregon, United States
    2 Biochemistry and Molecular Biology, Oregon Health & Science Univiersity, Portland, Oregon, United States
    3 Departments of Integrative Biosciences, Oregon Health Sciences University, Portland, Oregon, United States
  • Investigative Ophthalmology & Visual Science, December 2009, Vol. 50, No. 12. 5828-5836.

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