Publications2007

Contribution of calpains to photoreceptor cell death in N-methyl-N-nitrosourea-treated rats

  • Takayuki Oka1, Takeshi Nakajima1, Yoshiyuki Tamada1, Thomas R. Shearer2, Mitsuyoshi Azuma1.
    1 Senju Pharmaceutical Co., Ltd, 2 Oregon Health & Science University
  • Exp Neurol. 2007; 204(1): 39-48.

NMR analysis of ion pair formation between timolol and sorbic acid in ophthalmic preparations

  • M. Higashiyama1, K. Inada1, A. Ohtori1, K. Kakehi2.
    1 Senju Pharmaceutical Co., Ltd., 2 Kinki University
  • Journal of Pharmaceutical and Biomedical Analysis:43,1335-1342,2007.

PACAP Induces Neurite Outgrowth in Cultured Trigeminal Ganglion Cells and Recovery of Corneal Sensitivity After Flap Surgery in Rabbits

  • Chiho Fukiage1, Takeshi Nakajima1, Yoshiko Takayama1, Yoko Minagawa1, Thomas R. Shearer2, Azuma M1,2.
    1 Senju Pharmaceutical Co., Ltd., 2 Oregon Health & Science University
  • American Journal of Ophthalmology, 2007;143(2):255-262

Contribution of calpain to cellular damage in human retinal pigment epithelial cells cultured with zinc chelator

  • Yoshiyuki Tamada1, Ryan D. Walkup1, Thomas R. Shearer2, Mitsuyoshi Azuma1,2.
    1 Senju Pharmaceutical Co., Ltd. 2 Oregon Health & Science University
  • Current Eye Research, 32: 565-573, 2007

Effects of topical administration of Y-39983, a selective Rho-associated protein kinase inhibitor, on ocular tissues in rabbits and monkeys

  • Hideki Tokushige1, Masaru Inatani2, Shingo Nemoto1, Hideyuki Sakaki1, Koushirou Katayama3, Masayoshi Uehata3, and Hidenobu Tanihara2.
    1 Senju Pharmaceutical Co., Ltd, 2 Kumamoto University, 3 Mitsubishi Pharma Co., Ltd.
  • Invest Ophthalmol Vis Sci. 2007;48:3216-3222.

Corneal Critical Barrier against the Penetration of Dexamethasone and Lomefloxacin Hydrochloride: Evaluation by the Activation Energy for Drug Partition and Diffusion in Cornea.

  • Shin-ichi Yasueda, Masayo Higashiyama, Masazumi Yamaguchi, Akiharu Isowaki, and Akira Ohtori
  • Drug Dev Ind Pharm. 2007 Aug;33(8):805-811.

A new long acting ophthalmic solution of β-adrenergic antagonist based on ion-pair concept

  • Masayo Higashiyama, Akira Ohtori
    Senju Pharmaceutical Co., Ltd.
  • Drug Delivery System:22,162-166,2007.

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