2003

American Neurological Association 128th Annual Meeting and the 6th Annual Neurology Outcomes Symposium

• DAY:
• Place：San Francisco, USA.
• Analysis of Calcium-dependent Proteinase and Cytoskeletal Proteins in Muscle from Patients with Inflammatory Myopathy
• Ken-ya Murata1, Yoshiyuki Tamada1, Mitsuyoshi Azuma2 et. al.
  (Department of Neurology, Nara Medical University1、Senju Pharmaceutical Co. Ltd2)

Glaucoma Society International Congress of Ophthalmology

• DAY:
• Place：Chanitilly, France.
• Contribution of ROCK in contraction of trabecular meshwork: proposed mechanism for regulating aqueous outflow in monkey and human eye
• Emi Nakajima,　Takeshi Nakajima,　Yoko Minagawa,　Chie Mito,　Thomas R. Shearer and Mitsuyoshi Azuma

4th Retrometabolism Based Drug Design and Targeting Conference

• DAY:
• Place：Palm Coast, Florida (USA).
• Structure modification and formulation study of potent calpain inhibitor to improve intraocular availability
• Masayuki Nakamura,　Masazumi Yamaguchi,　Jun Inoue

Association for Research in Vision and Ophthalmology　(ARVO)　2003 Annual Meeting

• DAY:
• Place：Fort Lauderdale, Florida, U.S.A.
• ①Selenite May Cause Mitochondrial Damage and Cell Death in Cultured Lens Epithelial Cel
  ②Different Expression Patterns for Human Css1 and Css2 During Lens Maturation
  ③DNA Microarray Analysis of Lens Epithelial Cells in Selenite-injected Rats
  ④Activation of Downstream Pathways after Calpain-induced Proteolysis in the Hypoxic Rat Retina
  ⑤Role of Calpains in Hypoxia-Induced Cell Death in Monkey Retina
• ①M.Azuma,　T.Nakajima,　E.Nakajima,　T.R. Shearer
  ②H.Ma,　M.Shih,　E.Nakajima,　C.Fukiage,　M.Azuma,　T.R. Shearer
  ③T.Nakajima,　P.B. Belusko,　M.Azuma,　T.R. Shearer
  ④Y.Tamada,　E.Nakajima,　M.Azuma,　T.R. Shearer
  ⑤E.Nakajima,　Y.Tamada,　M.Azuma,　T.R. Shearer

Experimental Biology 2003 (EB 2003) Translating the Genome

• DAY:
• Place：San Diego, CA, U.S.A.
• ①Down-regulation of mitochondrial RNAs in rodent lens epithelial cells after injection of selenite
  ②Differential regulation of calpain proteolysis in primate lens and retina
• ①T.Nakajima,　P.B. Belusko,　M.Shih,　M.Azuma,　T.R. Shearer
  ②E.Nakajima,　P.B. Belusko,　C.Fukiage,　M.Azuma,　T.R. Shearer

FIRST SERI-ARVO MEETING ON RESEARCH IN VISION AND OPHTHALMOLOGY

• DAY:
• Place：SINGAPORE

《 Oral and Poster Presentations 》
Oral Presentation Date: February 9th , 2003
・ ECABET SODIUM
　○K. Masuda
　Effect of Topical Ecabet Sodium on Mucin Levels in the Tear Fluid of Patients with Dry Eye

《 Poster Presentation 》
・BEPOTASTINE BESILATE
　○T. Kida
　Effect of Bepotastine Besilate (TAU-284), a New Histamine H1Receptor Antagonist, on Experimental Histamine-induced and IgE-mediated Conjunctivitis

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