Meetings of the Minds2001

"The Calpain Gene Family in Health and Disease"

  • DAY: to be released
  • Place:Montana, U.S.A.
  • Lp82 calpain hydrolyzes other calpains in lens.
  • C. Fukiage (1,2), M. Azuma (1,2), Y.H. Kim (1), H. Ma (1), and T.R. Shearer(1)
    *(1): Oregon Health Sciences University, Portland, OR, U.S.A.
    *(2): Senju Pharmaceutical Co., Ltd. Beaverton, OR, U.S.A.

Association for Research in Vision and Ophthalmology (ARVO) 2001 Annual Meeting

  • DAY: to be released
  • Place:Fort Lauderdale, Florida, U.S.A.
  • ①Characterization of recombinant Rt88 from rat retina.
    ②Involvement of calpain isoforms in retinal degeneration in WBN/Kob rats.
    ③Different expression patterns for ubiquitous and p94 splice variants in monkey ocular tissues.
    ④Lens-directed, dominant negative for m-calpain suggests participation of multiple calpains in rodent cataract formation.
    ⑤Calpain inhibitor, SJA6017, reduces the rate of formation of selenite induced-cataract in rats.
    ⑥m-Calpain enhances heat-induced, in vitro light scattering by crystallins from non-rodent lenses.
    ⑦Unique cleavage sites on αA-crystallin identify relative activities of Lp82 and m-calpains in rat lens.
  • ①C. Fukiage, M. Azuma, T.R. Shearer
    ②K. Mizutani, Y. Tamada, C. Fukiage, M. Azuma, and T.R.Shearer
    ③T. Nakajima, C. Fukiage, M. Azuma, H. Ma, T.R. Shearer
    ④M. Azuma, C. Fukiage, Y. Tamada, Y. Nakamura, N. Forsberg, M. K. Duncan, T. R. Shearer
    ⑤Y. Tamada, C. Fukiage, K. Mizutani, M. Yamaguchi, Y. Nakamura, M. Azuma, T. R. Shearer
    ⑥M. Shih, L.L. David, K.J. Lampi, M. Azuma, T.R. Shearer
    ⑦T.R. Shearer, M. Shih, Y. Ueda, C. Fukiage, M. Azuma, L.L. David

Experimental Biology 2001
Annual Meeting of the American Society for Biochemistry and Molecular Biology (ASBMB)

  • DAY: to be released
  • Place:Orlando, FL, U.S.A.
  • The role of Lp82 in lens cataract formation.
  • C. Fukiage, M. Azuma, T. R. Shearer

3rd International Glaucoma Symposium

  • DAY: to be released
  • Place:Prague, Czech Republic
  • ROCK inhibitor:
    Effect of Rho-associated Protein Kinase Inhibitors on Ciliary Muscle and Trabecular Meshwork Contractility
  • Y. Kawamoto, Y. Yoshida, M. Waki, T. Fujii, and M. Azuma

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